Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p029 | Pregnancy | WCRB2014

IGF1 increases blastocyst attachment to endometrial epithelial cells in vitro and regulates fibronectin expression

Green Charmaine J , Fraser Stuart T , Day Margot L

Introduction: Implantation is a highly coordinated event in which the receptive endometrium is primed to receive adhesion-competent blastocysts. Implantation relies on the bridging of integrins on the endometrium and the blastocyst by extracellular matrix proteins, such as fibronectin. Factors produced in the female reproductive tract are thought to support development of the blastocyst to an adhesion competent state and to ensure coordination of blastocyst implantation abilit...